在线名词解释大全 - 抗菌药物耐药性 - 详细

Q1-Whichofthefollowingoptionsiscorrect?Thedevelopmentofanti-virulencestrategieshasbeenfavoredby:

A
A.1 - Increasing bacterial virulence.
B
B.2 - Increasing bacterial resistance to antibiotics and lower impact on host’s microbiota compared to antibiotics.
C
C.3 - Increased therapeutic effect of anti-virulence strategies as compared to antibiotics.
D
D.4 - Broad spectrum activity against pathogens.
正确答案:
The increasing bacterial resistance to antibiotics led to the development of alternative strategies, among which anti-virulence strategies. These ones target a specific virulence factor expressed by a specific pathogen, meaning that they should not affect commensals (which do not express the virulence factor), additionaly these strategies have a narrow spectrum activity.
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